Welcome to Evidence Corner. Here we try to explain the data behind the clinical decisions we make through deep-diving studies that have shaped how we treat patients with liver disease. For each clinical question, we’ve chosen a single study and with our digestible slides, we try to concisely highlight the key aspects of the study.
Fellow Lead
Faculty Editor
Learn how covid-19 vaccination affects outcomes in patients with liver disease
Does the stage of fibrosis predict outcomes in NAFLD?
https://pubmed.ncbi.nlm.nih.gov/34128254/
Ever received a consult about surgical risk stratification for a patient with cirrhosis. The VOCAL-Penn score tried to help most accurately predict the answer. The…
Heard about MELD 3.0 but not sure how it differs from MELD-Na? This is the paper that explains what MELD 3.0 is and how it…
Efficacy and safety of maralixibat treatment in patients with Alagille syndrome and cholestatic pruritus (ICONIC): a randomised phase 2 study – ScienceDirect Continuing on with…
If you were ever wondering why certain regimens are used in the treatment of AIH, here is the meta-analysis that helped determine the most effective…
In patients with chronic HBV infection, should HBV genotype be considered when determining who should undergo HCC surveillance? This trial tries to answer just that…
If you are curious if bariatric surgery is safe and effective in patients with NASH, this is the study for you. https://jamanetwork.com/journals/jama/article-abstract/2786270
Children are not small adults and thus their immune system is much more sophisticated… Check out the seminal iWITH trial establishing that in selected pediatric…
Fellow Lead
Faculty Editor
Do you have suggestions for topics within this series? Are you a fellow interested in contributing? Please feel free to reach out via Twitter to the fellow lead or to Liver Fellow Network directly. You can also e-mail us at liverfellownetwork@gmail.com.